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Brief clinical perspectives on the contemporary diagnosis and management of mental illness from top academic psychiatrists actively involved in both research and patient care.
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CLINICAL PRACTICE GUIDELINE WATCH
Safety Monitoring of Pharmacotherapy for Bipolar Disorder
- November 16, 2009
- Jonathan Silver, MD
Consensus-based guidelines from the International Society for Bipolar Disorders
- Reviewing:
- Ng F et al. Bipolar Disord 2009 Sep; 11:559
Recent Psychiatry Articles
SUMMARY AND COMMENT
Treating Post-CABG Depression via Telephone Care Management
- November 17, 2009
- Peter Roy-Byrne, MD
The collaborative care model for depression treatment shows its strength in a study of depressed cardiac patients.
- Reviewing:
- Rollman BL et al. JAMA 2009 Nov 18; 302:2095
FEATURE
Reviews of Note
- November 16, 2009
On cognitive enhancers, treatments for depression, prodromal signs of psychosis, gene–environment interactions, and addressing mutations in mitochondrial DNA
SUMMARY AND COMMENT
Using the Scientific Literature to Advance an Agenda
- November 12, 2009
- Peter Roy-Byrne, MD
This analysis of manufacturer-sponsored trials for off-label gabapentin use showed that the prespecified outcomes were not always reported.
- Reviewing:
- Vedula SS et al. N Engl J Med 2009 Nov 12; 361:1963
SUMMARY AND COMMENT
More on Adverse Effects of Antipsychotics on Children
- November 9, 2009
- Barbara Geller, MD
An observational study details metabolic changes after 12 weeks of treatment with atypical antipsychotics.
- Reviewing:
- Correll CU et al. JAMA 2009 Oct 28; 302:1765
SUMMARY AND COMMENT
More Evidence of Neurobiological Abnormalities in ADHD
- November 9, 2009
- Barbara Geller, MD
Deactivations of certain brain areas during a cognitive task were lacking in children with ADHD when untreated but not when on medication.
- Reviewing:
- Peterson BS et al. Am J Psychiatry 2009 Nov; 166:1286
SUMMARY AND COMMENT
Genetic Underpinnings of the Depression–Heart Disease Link
- November 9, 2009
- Peter Roy-Byrne, MD
Microvascular abnormalities and depression may share a genetic pathway.
- Reviewing:
- Vaccarino V et al. Arch Intern Med 2009 Oct 12; 169:1668
SUMMARY AND COMMENT
Deep Brain Stimulation: Slow Speed Ahead
- November 2, 2009
- Steven Dubovsky, MD
More needs to be learned about patient selection, electrode placement, and outcomes before routine clinical adoption of DBS for depression or OCD.
- Reviewing:
- Rabins P et al. Arch Gen Psychiatry 2009 Sep; 66:931
SUMMARY AND COMMENT
Phthalates and ADHD
- November 2, 2009
- Barbara Geller, MD
High levels of a common chemical are associated with ADHD symptoms. CME
- Reviewing:
- Kim B-N et al. Biol Psychiatry 2009 Nov 15; 66:958
SUMMARY AND COMMENT
Collaborative Care Improves Guideline Concordance for Bipolar Disorder
- November 2, 2009
- Joel Yager, MD
However, whether it improves outcomes remains unknown.
- Reviewing:
- Bauer MS et al. Am J Psychiatry 2009 Oct 1
SUMMARY AND COMMENT
Implications of Comorbid Anxiety for Prognosis of Bipolar Disorder
- November 2, 2009
- Joel Yager, MD
Anxiety adds to risks for subsequent depression in bipolar patients.
- Reviewing:
- Coryell W et al. Am J Psychiatry 2009 Oct 1
Editor's Picks from across Journal Watch
SUMMARY AND COMMENT
ADHD Medications Do Not Worsen Tics
- October 7, 2009
- By Martin T. Stein, MD
- Pediatrics and Adolescent Medicine
Some might actually eliminate tics. CME
- Reviewing:
- J Am Acad Child Adolesc Psychiatry 2009 Sep; 48:884
SUMMARY AND COMMENT
Why Parents Decide to Initiate, Continue, or Stop ADHD Treatment
- September 9, 2009
- By Martin T. Stein, MD
- Pediatrics and Adolescent Medicine
Multiple stressors and factors influence parents' decisions, including trials on and off medication. CME
- Reviewing:
- Pediatrics 2009 Aug; 124:580
SUMMARY AND COMMENT
Prenatal Exposure to SSRIs Can Adversely Affect Certain Delivery Outcomes
- October 22, 2009
- By Wendy S. Biggs, MD
- Women's Health
In utero SSRI exposure was associated with excess risk for preterm delivery and related complications but not for lower birth weight or smaller head circumference.
- Reviewing:
- Arch Pediatr Adolesc Med 2009 Oct; 163:949
SUMMARY AND COMMENT
Maintaining Mental Fitness in Old Age
- September 29, 2009
- By Kirk R. Daffner, MD
- Neurology
What factors affect maintenance of cognitive function or contribute to cognitive decline?
- Reviewing:
- Neurology 2009 Jun 9; 72:2029
Journal Watch Psychiatry summarizes important medical journal articles about a wide variety of psychiatric subjects including antidepressants, anxiety disorders, bipolar disorder, cognitive therapy, dementia, depression, psychotherapy, and schizophrenia.
