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You searched for: addiction in Psychiatry
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Imaging Internet Addiction in Teenagers
- April 12, 2013
- Barbara Geller, MD
- Psychiatry
Gaming-addicted adolescents show thinning of the orbitofrontal cortex.- Reviewing:
- Hong S-B et al., Behav Brain Funct 2013 Mar 12; 9:11.
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Addicted to Food
- May 17, 2010
- Steven Dubovsky, MD
- Psychiatry
A study in rats reveals dysfunction in the reward system with unlimited access to rich foods, similar to cocaine addictions.- Reviewing:
- Johnson PM and Kenny PJ., Nat Neurosci 2010 May; 13:635.
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Ghrelin: It's Not Just for Food; Let's Drink to That
- August 3, 2009
- Jonathan Silver, MD
- Psychiatry
In an animal study, central ghrelin signaling activates the mesolimbic reward system for alcohol.- Reviewing:
- Jerlhag E et al., Proc Natl Acad Sci U S A 2009 Jul 7; 106:11318.
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That Doughnut Is Addicting!
- June 25, 2007
- Steven Dubovsky, MD
- Psychiatry
An animal study demonstrates the pull of calorically dense foods.- Reviewing:
- Teegarden SL and Bale TL., Biol Psychiatry 2007 May 1; 61:1021-9.
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Heroin Injection vs. Methadone for Opioid Addiction
- August 19, 2009
- Peter Roy-Byrne, MD, and Richard Saitz, MD, MPH, FACP, FASAM
- Psychiatry
Prescribing the active ingredient in heroin provides superior outcomes but isn't feasible in the U.S. today.- Reviewing:
- Oviedo-Joekes E et al., N Engl J Med 2009 Aug 20; 361:777.
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Addiction Treatment and Pain
- December 22, 2008
- Deborah Cowley, MD
- Psychiatry
Persistent pain is associated with worse outcomes in veterans with non-opioid substance dependence.- Reviewing:
- Caldeiro RM et al., Addiction 2008 Dec; 103:1996.
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Insula: Another Brain Region Important for Addiction
- March 12, 2007
- Jonathan Silver, MD
- Psychiatry
A little-known area of the brain may mediate the urge to smoke.- Reviewing:
- Naqvi NH et al., Science 2007 Jan 26; 315:531-4.
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Treating Tobacco Addiction in Adolescents
- June 8, 2005
- Howard Bauchner, MD
- Psychiatry
Although the nicotine patch and nicotine gum are popular tools for treating tobacco addiction in adults, their use in adolescents is not well studied. In . . .- Reviewing:
- Moolchan ET et al., Pediatrics 2005 Apr; 115:e407-14.
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Vaccinating Against Heroin Addiction: A Promising Approach
- May 24, 2013
- Barbara Geller, MD
- Psychiatry
An animal study shows some benefits from a vaccine active against heroin and its metabolites.- Reviewing:
- Schlosburg JE et al., Proc Natl Acad Sci U S A 2013 May 6;:
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A Single Shot for Nicotine Addiction
- July 23, 2012
- Barbara Geller, MD
- Psychiatry
In animals, a vaccine using an adeno-associated viral vector that expresses high levels of an antinicotine antibody shows persistent effects.- Reviewing:
- Hicks MJ et al., Sci Transl Med 2012 Jun 27;:
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Treating the Molecular Biology of Cocaine Addiction
- September 20, 2010
- Steven Dubovsky, MD
- Psychiatry
Research in rats points to the possible therapeutic value of a selective inhibitor of aldehyde dehydrogenase-2.- Reviewing:
- Yao L et al., Nat Med 2010 Sep; 16:1024.
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A Molecular Switch for Chronic Cocaine Addiction
- January 7, 2008
- Peter Roy-Byrne, MD
- Psychiatry
An animal study provides important insights.- Reviewing:
- Renthal W et al., Neuron 2007 Nov 8; 56:517.
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A Genetic Component of Heroin Addiction
- June 21, 2006
- Barbara Geller, MD
- Psychiatry
A postmortem study focused on a polymorphism with effects in the striatum.- Reviewing:
- Drakenberg K et al., Proc Natl Acad Sci U S A 2006 May 16; 103:7883-8.
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Reviews of Note: An Update on the Neurobiology of Addiction
- February 22, 2006
- Steven Dubovsky, MD
- Psychiatry
Chronic overstimulation of dopaminergic centers appears to skew systems for brain reward and for planning. -
Genetic Polymorphisms Linked to Nicotine Addiction
- June 24, 2004
- Barbara Geller, MD
- Psychiatry
Twin and adoption studies have shown that genetic factors are involved in smoking initiation and dependence. Further, animal studies have shown that nicotine acts at . . .- Reviewing:
- Feng Y et al., Am J Hum Genet 2004 Jul; 75:112-21.
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Cognitive Basis of Denial in Addiction
- April 25, 2002
- Peter Roy-Byrne, MD
- Psychiatry
Denial of addiction is a common -- if not a core -- feature of most substance-use disorders and has been conceptualized as a mostly psychological . . .- Reviewing:
- Rinn W et al., J Neuropsychiatry Clin Neurosci 2002 Winter; 14:52-7.
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Integrating Primary Care and Addiction Care
- December 20, 2001
- Richard Saitz, MD, MPH
- Psychiatry
Although medical comorbidities are prevalent in patients with addictions, medical care and addiction care often are delivered separately and with little coordination. Results from 2 . . .- Reviewing:
- Weisner C et al., JAMA 2001 Oct 10; 286:
1715 1723 . Fiellin DA et al., JAMA 2001 Oct 10; 286:1724 1731 . Stein MD and Friedmann PD., JAMA 2001 Oct 10; 286:1764 1765 .
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Using Smokers' Genotypes to Predict Treatment Outcome
- December 3, 2012
- Barbara Geller, MD
- Psychiatry
A mathematical model using more than 12,000 single nucleotide polymorphisms predicts the likelihood of quitting smoking and of future substance use by teenagers.- Reviewing:
- Uhl GR et al., Mol Psychiatry 2012 Nov 6;:
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Gabapentin for Cannabis Dependence Free
- July 2, 2012
- Peter Roy-Byrne, MD
- Psychiatry
Commonly used for seizures, pain, and anxiety, gabapentin shows broad spectrum effects in patients with cannabis dependence.
CME Exam- Reviewing:
- Mason BJ et al., Neuropsychopharmacology 2012 Jun; 37:1689.
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Reducing the Adverse Impacts of Substance Abuse Free
- January 4, 2010
- Peter Roy-Byrne, MD
- Psychiatry
Neurobiology reveals the way to new treatments, but slowly.
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