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Antidepressants
Physician-authored summaries on the latest research on antidepressants, editorials on antidepressants, and perspectives on antidepressants - drawn from the top medical journals.
You searched for: antidepressants Items 1 to 20 of 384 results
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Are Add-On Antidepressants Ineffective for Bipolar Depression?Free!
- March 28, 2007
- Peter Roy-Byrne, MD
Antidepressants and placebo showed similar results when given adjunctively with mood stabilizers.- Covering:
- Sachs GS et al., N Engl J Med 2007 Mar 28;:
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Antidepressants: Which Patients Adhere to Treatment? Which Don't?
- April 5, 2006
- Nada L. Stotland, MD, MPH
Antidepressants are effective — but only if patients take them. Patients might not achieve a full therapeutic effect until 6 to 8 weeks of treatment, . . .- Covering:
- Olfson M et al., Am J Psychiatry 2006 Jan; 163:101-8.
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Polarity Switches in Bipolar Patients Taking Mood Stabilizers and Antidepressants
- March 22, 2006
- Joel Yager, MD
Specific antidepressants may pose different levels of risk for hypomania or mania in depressed bipolar patients.- Covering:
- Leverich GS et al., Am J Psychiatry 2006 Feb; 163:232-9.
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Cognitive Therapy Versus Antidepressants for More Severe Depressions
- June 22, 2005
- Steven Dubovsky, MD
Cognitive therapy (CT) and antidepressants are considered equally effective for all but severe forms of depression, for which antidepressants are preferred. In this study, researchers . . . CME Exam- Covering:
- DeRubeis RJ et al., Arch Gen Psychiatry 2005 Apr; 62:409-16.
- Hollon SD et al., Arch Gen Psychiatry 2005 Apr; 62:417-22.
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A Challenge to the Catecholamine Hypothesis of Antidepressants
- January 12, 2005
- Steven Dubovsky, MD
Conventional wisdom still clings to the notion that antidepressants act by inhibiting the reuptake of the indolamine serotonin or of the catecholamines norepinephrine and dopamine; . . .- Covering:
- Schroeder C et al., Clin Pharmacol Ther 2004 Nov; 76:480-9.
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Do Antidepressants Make Patients Suicidal?Free!
- January 29, 2007
- Steven Dubovsky, MD
Suicide attempts, but not suicides, may increase slightly, but the mechanism remains unclear. CME Exam- Covering:
- Tiihonen J et al., Arch Gen Psychiatry 2006 Dec; 63:1358-67.
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Antidepressants Cross the Placenta
- March 22, 2006
- Steven Dubovsky, MD
Cord blood levels of two tricyclics were close to maternal levels.- Covering:
- Loughhead AM et al., Biol Psychiatry 2006 Feb 1; 59:287-90.
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Direct-to-Consumer Advertising of Antidepressants and Prescribing Behavior
- June 8, 2005
- Peter Roy-Byrne, MD
How has the rapid growth of direct-to-consumer (DTC) advertisements of prescription drugs in the U.S. affected physicians' prescribing behavior? In this randomized, controlled trial, actors . . .- Covering:
- Kravitz RL et al., JAMA 2005 Apr 27; 293:1995-2002.
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Are “Dual-Neurotransmitter” Antidepressants Superior to SSRIs?
- February 11, 2008
- Steven Dubovsky, MD
This comprehensive meta-analysis suggests that the dual action drugs have a small edge, but the clinical usefulness of this statistical difference is unclear. CME Exam- Covering:
- Papakostas GI et al., Biol Psychiatry 2007 Dec 1; 62:1217.
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More News from STEP-BD: Adjunctive Antidepressants May Worsen Manic Symptoms
- November 5, 2007
- Joel Yager, MD
Observations from a naturalistic cohort study- Covering:
- Goldberg JF et al., Am J Psychiatry 2007 Sep; 164:1348.
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Antidepressants in Pediatric Patients: Benefits Might Outweigh RisksFree!
- April 17, 2007
- Peter Roy-Byrne, MD
SSRIs still have their uses, despite suicidality risks and less prescribing for children.- Covering:
- Bridge JA et al., JAMA 2007 Apr 18; 297:1683-96.
- Nemeroff CB et al., Arch Gen Psychiatry 2007 Apr; 64:466-72.
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Antidepressants in Pregnancy: The Ongoing StoryFree!
- December 29, 2006
The optimal approach for pregnant women with severe or longstanding depression may be to continue antidepressant treatment, but risks to fetuses are emerging. -
Depression and Antidepressants in Children: Scylla and Charybdis?Free!
- December 29, 2006
As more data arrive, steering in these turbulent waters becomes more difficult. -
Do Antidepressants Induce Hypomania in Unipolar Patients?
- October 30, 2006
- Steven Dubovsky, MD
Perhaps, but these patients might merit a bipolar diagnosis.- Covering:
- Wada K et al., J Clin Psychopharmacol 2006 Oct; 26:512-5.
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Comparing Suicide Risk with Antidepressants in Children and AdultsFree!
- August 28, 2006
- Barbara Geller, MD
Among hospitalized Medicaid recipients, the risk may be greater in children and adolescents.- Covering:
- Olfson M et al., Arch Gen Psychiatry 2006 Aug; 63:865-72.
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Light Therapy or Antidepressants for Seasonal Affective Disorder?
- June 7, 2006
- Thomas L. Schwenk, MD
A head-to-head trial showed equal efficacy for these therapies.- Covering:
- Lam RW et al., Am J Psychiatry 2006 May; 163:805-12.
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Do Antidepressants Increase Suicidality in Younger Patients?
- April 19, 2006
- Steven Dubovsky, MD
How the FDA developed its warnings- Covering:
- Hammad TA et al., Arch Gen Psychiatry 2006 Mar; 63:332-9.
- Baldessarini RJ et al., Arch Gen Psychiatry 2006 Mar; 63:246-8.
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Suicidality and Antidepressants: Was the FDA Right?
- February 22, 2006
- Joel Yager, MD
The FDA may have been overly cautious, but close monitoring of all depressed patients for suicidality makes good clinical sense.- Covering:
- Simon GE et al., Am J Psychiatry 2006 Jan; 163:41-7.
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Are Antidepressants Good for Your Heart?
- August 17, 2005
- Steven Dubovsky, MD
Major depression occurs in 20% of patients after myocardial infarction (MI) and increases the subsequent risk for mortality as much as most other medical risk . . .- Covering:
- Taylor CB et al., Arch Gen Psychiatry 2005 Jul; 62:792-8.
- Glassman AH., Arch Gen Psychiatry 2005 Jul; 62:711-2.
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Are Antidepressants Less Effective in Women Than in Men?
- February 9, 2005
- Nada L. Stotland, MD, MPH
The failure of antidepressant medications to live up to therapeutic promises has drawn considerable media attention recently. Uncertainty about antidepressant efficacy places additional burdens on . . .- Covering:
- Khan A et al., Am J Psychiatry 2004 Nov; 161:2045-9.
You searched for: antidepressants Items 1 to 20 of 384 results