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Search for Bipolar Disorder in Psychiatry
Physician-authored summaries on the latest research on bipolar disorder, editorials on bipolar disorder, and perspectives on bipolar disorder - drawn from the top medical journals.
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You searched for: bipolar disorder in Psychiatry
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The Bipolar/Schizophrenia Border Continues to Widen
- May 7, 2012
- Steven Dubovsky, MD
- Psychiatry
Shared neurodevelopmental factors may reflect overlapping and genetically determined liabilities to features common to both disorders.- Reviewing:
- Hulshoff Pol HE et al., Arch Gen Psychiatry 2012 Apr; 69:349.
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Anxiety Increases Impulsivity in Patients with Mood Disorders
- April 9, 2012
- Deborah Cowley, MD
- Psychiatry
Knowing this link can help clinicians who are assessing patients' risks for impulsive behaviors and suicidality.- Reviewing:
- Bellani M et al., J Psychiatr Res 2012 Feb 13;:
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Antiepileptics May Not Elevate Suicide Risk in Patients with Bipolar Disorder Free
- January 23, 2012
- Joel Yager, MD
- Psychiatry
A 30-year observational study showed no rise in risk for suicidal behaviors when antiepileptic medications were used.- Reviewing:
- Leon AC et al., Am J Psychiatry 2011 Dec 15;:
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Difficult-to-Treat Depressed Patients May Be Bipolar
- January 23, 2012
- Peter Roy-Byrne, MD
- Psychiatry
Results based on analyses of a large national database validate clinician impressions that medication-nonresponsive depressed patients may have bipolar illness, often with atypical manifestations.- Reviewing:
- Li C-T et al., Br J Psychiatry 2012 Jan; 200:45.
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Lithium or Valproate for Preventing Suicidal Behavior in Patients with Bipolar Disorder?
- August 22, 2011
- Joel Yager, MD
- Psychiatry
The two mood stabilizers yielded similar rates of suicidal behaviors and events.- Reviewing:
- Oquendo MA et al., Am J Psychiatry 2011 Jul 18;:
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More Insight into the Pathophysiology of Bipolar Disorder
- April 4, 2011
- Steven Dubovsky, MD
- Psychiatry
A polymorphism in some patients contributes to the well-characterized altered calcium ion signaling in bipolar disorder, which may become a new research focus.- Reviewing:
- Machado-Vieira R et al., Biol Psychiatry 2011 Feb 15; 69:344.
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Illness Course in Women with Bipolar Disorder Free
- March 14, 2011
- Joel Yager, MD
- Psychiatry
Premenstrual exacerbations are associated with a more difficult course of bipolar illness.
CME Exam- Reviewing:
- Dias RS et al., Am J Psychiatry 2011 Feb 15;:
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Does Bipolar Disorder Contribute to Violence?
- November 1, 2010
- Steven Dubovsky, MD
- Psychiatry
No, but substance abuse does.
CME Exam- Reviewing:
- Fazel S et al., Arch Gen Psychiatry 2010 Sep; 67:931.
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Bipolar Disorder and Schizophrenia — Both Bad for Your Brain
- August 9, 2010
- Steven Dubovsky, MD
- Psychiatry
Affected brain regions are associated with executive function, other cognitive processes, and psychosis.- Reviewing:
- Rimol LM et al., Biol Psychiatry 2010 Jul 1; 68:41.
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Gender Matters in the Course of Bipolar Illness
- July 2, 2010
- Joel Yager, MD
- Psychiatry
Higher rates of both rapid cycling and anxiety disorders among bipolar women help to account for their greater rates of depression.- Reviewing:
- Altshuler LL et al., Am J Psychiatry 2010 Jun; 167:708.
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Bipolar Disorder plus Antisocial Personality Disorder: An Impulsive Storm
- June 7, 2010
- Joel Yager, MD
- Psychiatry
Talk about impulsivity! Comorbid bipolar disorder and antisocial personality disorder- Reviewing:
- Swann AC et al., Acta Psychiatr Scand 2010 Jun; 121:453.
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Gray Matter and Lithium Treatment
- April 16, 2010
- Peter Roy-Byrne, MD
- Psychiatry
This MRI study identifies a possible mechanism for lithium's therapeutic effect in patients with bipolar disorder.
CME Exam- Reviewing:
- Lyoo IK et al., Neuropsychopharmacology 2010 Mar 31;:
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Substance Use Disorders and the Course of Bipolar Disorder
- January 25, 2010
- Joel Yager, MD
- Psychiatry
Comorbid substance use disorder increases the risk that a depressive episode will switch to mania or hypomania, but may have few effects on recovery.- Reviewing:
- Ostacher MJ et al., Am J Psychiatry 2009 Dec 15;:
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Collaborative Care Improves Guideline Concordance for Bipolar Disorder
- November 2, 2009
- Joel Yager, MD
- Psychiatry
However, whether it improves outcomes remains unknown.- Reviewing:
- Bauer MS et al., Am J Psychiatry 2009 Oct 1;:
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Implications of Comorbid Anxiety for Prognosis of Bipolar Disorder
- November 2, 2009
- Joel Yager, MD
- Psychiatry
Anxiety adds to risks for subsequent depression in bipolar patients.- Reviewing:
- Coryell W et al., Am J Psychiatry 2009 Oct 1;:
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A Polygenic Basis for Major Disorders?
- August 10, 2009
- Barbara Geller, MD
- Psychiatry
Common polymorphisms that individually exert small effects might, as a group, play a substantial genetic role.- Reviewing:
- Purcell SM et al. for the International Schizophrenia Consortium., Nature 2009 Jul 1;: Shi J et al., Nature 2009 Jul 1;: Stefansson H et al., Nature 2009 Jul 1;:
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Schizophrenia and Bipolar Disorder Run in the Same Families
- August 10, 2009
- Steven Dubovsky, MD
- Psychiatry
A meta-analysis of familial coaggregation studies yields positive results.- Reviewing:
- Van Snellenberg JX and de Candia T., Arch Gen Psychiatry 2009 Jul; 66:748.
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Manic Symptoms in Bipolar Depression: Prevalence and Significance
- February 23, 2009
- Joel Yager, MD
- Psychiatry
Watch out for this underappreciated but common phenomenon.- Reviewing:
- Goldberg JF et al., Am J Psychiatry 2009 Feb; 166:173. Frye MA et al., Am J Psychiatry 2009 Feb; 166:164.
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Schizophrenia and Bipolar Illness: Common Genetic Origins
- February 9, 2009
- Peter Roy-Byrne, MD
- Psychiatry
Swedish national registers provide clearer answers to an old controversy.- Reviewing:
- Lichtenstein P et al., Lancet 2009 Jan 17; 373:234.
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A Larger Look at the Genetics of Bipolar Disorder
- September 15, 2008
- Barbara Geller, MD
- Psychiatry
By combining the findings of three separate association studies, researchers identify two strong associations.- Reviewing:
- Ferreira MAR et al., Nat Genet 2008 Aug 17;:
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