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Search for Schizophrenia in Psychiatry
Physician-authored summaries on the latest research on schizophrenia, editorials on schizophrenia, and perspectives on schizophrenia - drawn from the top medical journals.
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You searched for: schizophrenia in Psychiatry
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How Relapses and Treatment Affect Brain Volume in Schizophrenia
- April 22, 2013
- Joel Yager, MD
- Psychiatry
Total relapse duration and greater medication intensity are associated with greater loss of brain tissue.- Reviewing:
- Andreasen NC et al., Am J Psychiatry 2013 Apr 5;:
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Oxytocin, Schizophrenia, Social Recognition, and Odor Identification: Nothing to Sneeze At
- March 18, 2013
- Jonathan Silver, MD
- Psychiatry
Two studies demonstrate biological effects, but no significant change in clinical symptoms.- Reviewing:
- Fischer-Shofty M et al., Schizophr Res 2013 Feb 19;: Lee MR et al., Schizophr Res 2013 Apr; 145:110.
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Schizophrenia, Substance Use, and Violence: Adding Fuel to the Fire
- February 25, 2013
- Joel Yager, MD
- Psychiatry
Although schizophrenia itself increased the likelihood of a violent-offense conviction, comorbid substance use more than tripled the risk.- Reviewing:
- Short T et al., Acta Psychiatr Scand 2013 Feb 4;:
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Perinatal Choline for Infants with a Schizophrenia Risk Gene
- February 15, 2013
- Barbara Geller, MD
- Psychiatry
Infants with the risk allele who received placebo had a schizophrenia endophenotype, but not infants receiving choline.- Reviewing:
- Ross RG et al., Am J Psychiatry 2013 January 15;:
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Is Schizophrenia a Neuroinflammatory Disorder?
- February 11, 2013
- Peter Roy-Byrne, MD
- Psychiatry
Ten percent of acutely ill schizophrenia patients have antibodies against NMDA glutamate receptors, compared with 3% of depression patients and no patients with borderline personality disorder.- Reviewing:
- Steiner J et al., JAMA Psychiatry 2013 Jan 23;:
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Muscle Fitness Is Diminished in Schizophrenia
- January 28, 2013
- Joel Yager, MD
- Psychiatry
A study showing reduced muscle fitness and walking capacity in patients with schizophrenia points to a simple intervention.- Reviewing:
- Vancampfort D et al., BMC Psychiatry 2013 Jan 3; 13:5.
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How Cannabis Might Increase Schizophrenia Risk in the Developing Mind
- December 21, 2012
- Barbara Geller, MD
- Psychiatry
In adolescent mice, a cannabinoid receptor agonist is linked to abnormal prepulse inhibition similar to that found in schizophrenia.- Reviewing:
- Gleason KA et al., Transl Psychiatry 2012 Nov 27; 2:e199.
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Links Between Toxoplasmosis and Schizophrenia
- December 3, 2012
- Joel Yager, MD
- Psychiatry
Schizophrenic patients with toxoplasmosis may have greater disease burdens, but this study draws a murky picture.- Reviewing:
- Holub D et al., Acta Psychiatr Scand 2012 Nov 5;:
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Increased Risk for Nonfamilial Schizophrenia from De Novo Mutations
- October 29, 2012
- Barbara Geller, MD
- Psychiatry
Identifying these pathways is a step toward targeted pharmacotherapy.- Reviewing:
- Xu B et al., Nat Genet 2012 Oct 3;:
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In Schizophrenia, Drug Response and Resistance Are Linked to Dopamine Synthesis
- October 29, 2012
- Joel Yager, MD
- Psychiatry
Differing capacity for striatal dopamine synthesis might reflect clinically meaningful schizophrenia subtypes.- Reviewing:
- Demjaha A et al., Am J Psychiatry 2012 Oct 3;:
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Low GABA Neuronal Markers Characterize a Subset of Schizophrenia Patients
- October 15, 2012
- Joel Yager, MD
- Psychiatry
This finding might eventually contribute to new approaches toward personalized medicine.- Reviewing:
- Volk DW et al., Am J Psychiatry 2012 Oct 1; 169:1082.
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Metformin for Antipsychotic-Induced Adverse Effects in Women with Schizophrenia
- July 9, 2012
- Joel Yager, MD
- Psychiatry
The medication reversed amenorrhea, promoted weight loss, and improved insulin resistance.- Reviewing:
- Wu R-R et al., Am J Psychiatry 2012 Jun 15;:
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Treating to a TT: Genotyping for Drug Response in Schizophrenia
- July 2, 2012
- Barbara Geller, MD
- Psychiatry
A genetic polymorphism related to brain potassium ion channels is associated with significantly better response to atypical antipsychotics.- Reviewing:
- Apud JA et al., Am J Psychiatry 2012 Jun 15;:
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Maintenance Antipsychotics for Schizophrenia: Yes, But . . .
- June 4, 2012
- Peter Roy-Byrne, MD
- Psychiatry
A comprehensive meta-analysis confirms effectiveness for most patients but provides limited information about response predictors so that individualized treatment remains more art than science.- Reviewing:
- Leucht S et al., Lancet 2012 Jun 2; 379:2063.
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The Bipolar/Schizophrenia Border Continues to Widen
- May 7, 2012
- Steven Dubovsky, MD
- Psychiatry
Shared neurodevelopmental factors may reflect overlapping and genetically determined liabilities to features common to both disorders.- Reviewing:
- Hulshoff Pol HE et al., Arch Gen Psychiatry 2012 Apr; 69:349.
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Cognitive Therapy for Schizophrenia Free
- March 19, 2012
- Steven Dubovsky, MD
- Psychiatry
Even chronically ill, poorly functioning patients can benefit from this approach.
CME Exam- Reviewing:
- Grant PM et al., Arch Gen Psychiatry 2012 Feb; 69:121.
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Preexisting Autoimmune Disease and Severe Infection Increase Schizophrenia Risk
- January 9, 2012
- Joel Yager, MD
- Psychiatry
The combination particularly increases risk.- Reviewing:
- Benros ME et al., Am J Psychiatry 2011 Dec 1; 168:1303.
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Multiorgan Dysfunction Contributes to Premature Mortality in Schizophrenia
- September 19, 2011
- Joel Yager, MD
- Psychiatry
Schizophrenia patients in the ICU are younger than other ICU patients and are at greater risk for death.- Reviewing:
- Shen H-N et al., Psychosom Med 2011 Aug 23;:
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A SNP for the Increased Risk for Diabetes in Schizophrenia
- July 25, 2011
- Steven Dubovsky, MD
- Psychiatry
An allele that is frequently associated with diabetes risk is found to have elevated prevalence in schizophrenia patients.- Reviewing:
- Hansen T et al., Biol Psychiatry 2011 Jul 1; 70:59.
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Herpes Simplex Virus 1 Exposure May Affect the Course of Schizophrenia
- June 20, 2011
- Joel Yager, MD
- Psychiatry
Seropositive patients with schizophrenia showed worsened cognition and decreased gray matter in the posterior cingulate gyrus.- Reviewing:
- Prasad KM et al., Am J Psychiatry 2011 Jun 1;:
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