Psychiatry: Archives

SUMMARY AND COMMENT

Treating Post-CABG Depression via Telephone Care Management

• November 17, 2009
• Peter Roy-Byrne, MD

The collaborative care model for depression treatment shows its strength in a study of depressed cardiac patients.

• Reviewing:
• Rollman BL et al., JAMA 2009 Nov 18; 302:2095

FEATURE

Reviews of Note

• November 16, 2009

On cognitive enhancers, treatments for depression, prodromal signs of psychosis, gene–environment interactions, and addressing mutations in mitochondrial DNA

• Reviewing:
• Lehrer J., Nature 2009 Oct 15; 461:862 March JS and Vitiello B., Am J Psychiatry 2009 Oct; 166:1118 Cuijpers P et al., J Clin Psychiatry 2009 Sep; 70:1219 Nelson JC and Papakostas GI., Am J Psychiatry 2009 Sep; 166:980 McGorry PD et al., J Clin Psychiatry 2009 Sep; 70:1206 Wegman HL and Stetler C., Psychosom Med 2009 Oct; 71:805 Friston KJ., Science 2009 Oct 16; 326:399 Belsky J et al., Mol Psychiatry 2009 Aug; 14:746 Tachibana M et al., Nature 2009 Sep 17; 461:367

CLINICAL PRACTICE GUIDELINE WATCH

Safety Monitoring of Pharmacotherapy for Bipolar Disorder

• November 16, 2009
• Jonathan Silver, MD

Consensus-based guidelines from the International Society for Bipolar Disorders

• Reviewing:
• Ng F et al., Bipolar Disord 2009 Sep; 11:559

SUMMARY AND COMMENT

Using the Scientific Literature to Advance an Agenda

• November 12, 2009
• Peter Roy-Byrne, MD

This analysis of manufacturer-sponsored trials for off-label gabapentin use showed that the prespecified outcomes were not always reported.

• Reviewing:
• Vedula SS et al., N Engl J Med 2009 Nov 12; 361:1963

SUMMARY AND COMMENT

More on Adverse Effects of Antipsychotics on Children

• November 9, 2009
• Barbara Geller, MD

An observational study details metabolic changes after 12 weeks of treatment with atypical antipsychotics.

• Reviewing:
• Correll CU et al., JAMA 2009 Oct 28; 302:1765 Varley CK and McClellan J., JAMA 2009 Oct 28; 302:1811

SUMMARY AND COMMENT

More Evidence of Neurobiological Abnormalities in ADHD

• November 9, 2009
• Barbara Geller, MD

Deactivations of certain brain areas during a cognitive task were lacking in children with ADHD when untreated but not when on medication.

• Reviewing:
• Peterson BS et al., Am J Psychiatry 2009 Nov; 166:1286

SUMMARY AND COMMENT

Genetic Underpinnings of the Depression–Heart Disease Link

• November 9, 2009
• Peter Roy-Byrne, MD

Microvascular abnormalities and depression may share a genetic pathway.

• Reviewing:
• Vaccarino V et al., Arch Intern Med 2009 Oct 12; 169:1668

SUMMARY AND COMMENT

Deep Brain Stimulation: Slow Speed Ahead

• November 2, 2009
• Steven Dubovsky, MD

More needs to be learned about patient selection, electrode placement, and outcomes before routine clinical adoption of DBS for depression or OCD.

• Reviewing:
• Rabins P et al., Arch Gen Psychiatry 2009 Sep; 66:931

SUMMARY AND COMMENT

Phthalates and ADHD

• November 2, 2009
• Barbara Geller, MD

High levels of a common chemical are associated with ADHD symptoms. CME

• Reviewing:
• Kim B-N et al., Biol Psychiatry 2009 Nov 15; 66:958

SUMMARY AND COMMENT

Collaborative Care Improves Guideline Concordance for Bipolar Disorder

• November 2, 2009
• Joel Yager, MD

However, whether it improves outcomes remains unknown.

• Reviewing:
• Bauer MS et al., Am J Psychiatry 2009 Oct 1