An Association Between Childhood IQ and Cortical Thickness in Elders
SUMMARY AND COMMENT
The inclusion of academic test results in medical records may help future researchers looking at variations in cortical thickness in old age.
Reviewing:
Karama S et al., Mol Psychiatry 2013 Jun 4
ADHD from Childhood into Adulthood: A 13-Year Imaging Follow-Up
SUMMARY AND COMMENT
Cortical trajectories differ between adults who continue to have attention-deficit/hyperactivity disorder versus those who have outgrown their childhood diagnoses.
Reviewing:
Shaw P et al, Biol Psychiatry 2013 May 30
Relapse Prevention for Recurrent Major Depression: CBT or Psychoeducation?
SUMMARY AND COMMENT
June 17, 2013
Joel Yager, MD
After initial remission, cognitive-behavioral therapy was associated with fewer relapses, but only in patients with five or more prior episodes.
Reviewing:
Stangier U et al., Am J Psychiatry 2013 Jun; 170:624
Delusions That Lead to Violence
SUMMARY AND COMMENT
The presence of anger strengthens the association between delusions and serious violence in patients with first-episode psychosis.
Reviewing:
Coid JW et al., JAMA Psychiatry 2013 May 1
Neuregulin 1 May Have a Large Role in Schizophrenia
SUMMARY AND COMMENT
June 10, 2013
Joel Yager, MD
In transgenic mice overexpressing neuregulin 1, normalizing expression reverses schizophrenia-like deficits.
Reviewing:
Yin D-M et al., Neuron 2013 May 22; 78:644
All Psychotherapies Equally Effective for Depression
SUMMARY AND COMMENT
In a large network meta-analysis, seven psychotherapies show at least small effect sizes compared with control conditions, but almost no differences in head-to-head comparisons.
Reviewing:
Barth J et al., PLoS Med 2013 May 28; 10:e1001454
Cannabinoid System Dysregulation in PTSD
SUMMARY AND COMMENT
Patients with posttraumatic stress disorder have more cannabinoid receptors and fewer endocannabinoids in plasma than people without the disorder.
Reviewing:
Neumesiter A et al., Mol Psychiatry 2013 May 14
Prepartum Blood Test Predicts Postpartum Depression Risk
SUMMARY AND COMMENT
The extent of estrogen-induced DNA methylation in the blood cells of pregnant women with mood-disorder histories is associated with postpartum depression.
Reviewing:
Guintivano J et al., Mol Psychiatry 2013 May 21
Cognitive Processing Therapy in African Victims of Sexual Violence
SUMMARY AND COMMENT
In Congolese villages, female victims of sexual violence showed significant benefit from an adaptation of this evidence-based psychotherapy.
Reviewing:
Bass JK et al., N Engl J Med 2013 Jun 6; 368:2182
Adding CBT to SSRIs for Older Patients with Generalized Anxiety Disorder
SUMMARY AND COMMENT
After acute antidepressant treatment, augmentation with cognitive-behavioral therapy reduces relapse in this patient population.
Reviewing:
Wetherell JL et al., Am J Psychiatry 2013 May 17