Treating Post-CABG Depression via Telephone Care Management
SUMMARY AND COMMENT
The collaborative care model for depression treatment shows its strength in a study of depressed cardiac patients.
Reviewing:
Rollman BL et al., JAMA 2009 Nov 18; 302:2095
Reviews of Note
FEATURE
On cognitive enhancers, treatments for depression, prodromal signs of psychosis, gene–environment interactions, and addressing mutations in mitochondrial DNA
Reviewing:
Lehrer J., Nature 2009 Oct 15; 461:862
March JS and Vitiello B., Am J Psychiatry 2009 Oct; 166:1118
Cuijpers P et al., J Clin Psychiatry 2009 Sep; 70:1219
Nelson JC and Papakostas GI., Am J Psychiatry 2009 Sep; 166:980
McGorry PD et al., J Clin Psychiatry 2009 Sep; 70:1206
Wegman HL and Stetler C., Psychosom Med 2009 Oct; 71:805
Friston KJ., Science 2009 Oct 16; 326:399
Belsky J et al., Mol Psychiatry 2009 Aug; 14:746
Tachibana M et al., Nature 2009 Sep 17; 461:367
Safety Monitoring of Pharmacotherapy for Bipolar Disorder
CLINICAL PRACTICE GUIDELINE WATCH
Consensus-based guidelines from the International Society for Bipolar Disorders
Reviewing:
Ng F et al., Bipolar Disord 2009 Sep; 11:559
Using the Scientific Literature to Advance an Agenda
SUMMARY AND COMMENT
This analysis of manufacturer-sponsored trials for off-label gabapentin use showed that the prespecified outcomes were not always reported.
Reviewing:
Vedula SS et al., N Engl J Med 2009 Nov 12; 361:1963
More on Adverse Effects of Antipsychotics on Children
SUMMARY AND COMMENT
An observational study details metabolic changes after 12 weeks of treatment with atypical antipsychotics.
Reviewing:
Correll CU et al., JAMA 2009 Oct 28; 302:1765
Varley CK and McClellan J., JAMA 2009 Oct 28; 302:1811
More Evidence of Neurobiological Abnormalities in ADHD
SUMMARY AND COMMENT
Deactivations of certain brain areas during a cognitive task were lacking in children with ADHD when untreated but not when on medication.
Reviewing:
Peterson BS et al., Am J Psychiatry 2009 Nov; 166:1286
Genetic Underpinnings of the Depression–Heart Disease Link
SUMMARY AND COMMENT
Microvascular abnormalities and depression may share a genetic pathway.
Reviewing:
Vaccarino V et al., Arch Intern Med 2009 Oct 12; 169:1668
Deep Brain Stimulation: Slow Speed Ahead
SUMMARY AND COMMENT
More needs to be learned about patient selection, electrode placement, and outcomes before routine clinical adoption of DBS for depression or OCD.
Reviewing:
Rabins P et al., Arch Gen Psychiatry 2009 Sep; 66:931
Phthalates and ADHD
SUMMARY AND COMMENT
High levels of a common chemical are associated with ADHD symptoms.
CME
Reviewing:
Kim B-N et al., Biol Psychiatry 2009 Nov 15; 66:958
Collaborative Care Improves Guideline Concordance for Bipolar Disorder
SUMMARY AND COMMENT
November 2, 2009
Joel Yager, MD
However, whether it improves outcomes remains unknown.
Reviewing:
Bauer MS et al., Am J Psychiatry 2009 Oct 1