Phthalates and ADHD
SUMMARY AND COMMENT
High levels of a common chemical are associated with ADHD symptoms.
Reviewing:
Kim B-N et al., Biol Psychiatry 2009 Nov 15; 66:958
Deep Brain Stimulation: Slow Speed Ahead
SUMMARY AND COMMENT
More needs to be learned about patient selection, electrode placement, and outcomes before routine clinical adoption of DBS for depression or OCD.
Reviewing:
Rabins P et al., Arch Gen Psychiatry 2009 Sep; 66:931
Collaborative Care Improves Guideline Concordance for Bipolar Disorder
SUMMARY AND COMMENT
November 2, 2009
Joel Yager, MD
However, whether it improves outcomes remains unknown.
Reviewing:
Bauer MS et al., Am J Psychiatry 2009 Oct 1
Implications of Comorbid Anxiety for Prognosis of Bipolar Disorder
SUMMARY AND COMMENT
November 2, 2009
Joel Yager, MD
Anxiety adds to risks for subsequent depression in bipolar patients.
Reviewing:
Coryell W et al., Am J Psychiatry 2009 Oct 1
Depression Is Bad for Your Heart
SUMMARY AND COMMENT
And attaining remission significantly improves mortality risk in patients with acute coronary syndromes.
Reviewing:
Glassman AH et al., Arch Gen Psychiatry 2009 Sep; 66:1022
Copy Number Variations and Neurobehavioral Diagnoses
SUMMARY AND COMMENT
Further research into the effects of rare CNVs
Reviewing:
Guilmatre A et al., Arch Gen Psychiatry 2009 Sep; 66:947
Xu B et al., Proc Natl Acad Sci U S A 2009 Sep 11
Genetic Risk Factors for Post-Traumatic Stress Disorder
SUMMARY AND COMMENT
A genetic study finds strong connections between PTSD and genes that regulate activity in the glucocorticoid receptor.
Reviewing:
Yehuda R et al., Biol Psychiatry 2009 Oct 1; 66:708
Treating Depressed Cardiac Patients? Omega-3s Don't Help the Depression
SUMMARY AND COMMENT
Omega-3 fatty acids do not appear to augment the effects of sertraline in depressed patients with cardiac disease.
Reviewing:
Carney RM et al., JAMA 2009 Oct 21; 302:1651
Gabapentin for Alcohol Withdrawal
SUMMARY AND COMMENT
A high dose was at least as effective as lorazepam in outpatients with moderate withdrawal symptoms.
Reviewing:
Myrick H et al., Alcohol Clin Exp Res 2009 Sep; 33:1582
More About SSRI Use During Pregnancy
SUMMARY AND COMMENT
A population-based cohort study reports SSRI-associated cardiac septal defects.
Reviewing:
Pedersen LH et al., BMJ 2009 Sep 23; 339:b3569
Chambers C., BMJ 2009 Sep 23; 339:b3525