Implications of Comorbid Anxiety for Prognosis of Bipolar Disorder
SUMMARY AND COMMENT
November 2, 2009
Joel Yager, MD
Anxiety adds to risks for subsequent depression in bipolar patients.
Reviewing:
Coryell W et al., Am J Psychiatry 2009 Oct 1
Copy Number Variations and Neurobehavioral Diagnoses
SUMMARY AND COMMENT
Further research into the effects of rare CNVs
Reviewing:
Guilmatre A et al., Arch Gen Psychiatry 2009 Sep; 66:947
Xu B et al., Proc Natl Acad Sci U S A 2009 Sep 11
Depression Is Bad for Your Heart
SUMMARY AND COMMENT
And attaining remission significantly improves mortality risk in patients with acute coronary syndromes.
Reviewing:
Glassman AH et al., Arch Gen Psychiatry 2009 Sep; 66:1022
Genetic Risk Factors for Post-Traumatic Stress Disorder
SUMMARY AND COMMENT
A genetic study finds strong connections between PTSD and genes that regulate activity in the glucocorticoid receptor.
Reviewing:
Yehuda R et al., Biol Psychiatry 2009 Oct 1; 66:708
Treating Depressed Cardiac Patients? Omega-3s Don't Help the Depression
SUMMARY AND COMMENT
Omega-3 fatty acids do not appear to augment the effects of sertraline in depressed patients with cardiac disease.
Reviewing:
Carney RM et al., JAMA 2009 Oct 21; 302:1651
Gabapentin for Alcohol Withdrawal
SUMMARY AND COMMENT
A high dose was at least as effective as lorazepam in outpatients with moderate withdrawal symptoms.
Reviewing:
Myrick H et al., Alcohol Clin Exp Res 2009 Sep; 33:1582
More About SSRI Use During Pregnancy
SUMMARY AND COMMENT
A population-based cohort study reports SSRI-associated cardiac septal defects.
Reviewing:
Pedersen LH et al., BMJ 2009 Sep 23; 339:b3569
Chambers C., BMJ 2009 Sep 23; 339:b3525
Do Antidepressants Quickly Reverse Negative Affective Biases?
SUMMARY AND COMMENT
October 19, 2009
Joel Yager, MD
Antidepressants may have an immediate psychological effect.
Reviewing:
Harmer CJ et al., Am J Psychiatry 2009 Oct; 166:1178
Two Treatment Methods Compared for Borderline Personality Disorder
SUMMARY AND COMMENT
October 19, 2009
Joel Yager, MD
In a head-to-head trial, both dialectical behavior therapy and psychiatric management according to the APA's Practice Guidelines reduce symptoms and self-harm behaviors.
Reviewing:
McMain SF et al., Am J Psychiatry 2009 Sep 15
Inflammatory Proteins: The Body–Brain Connection
SUMMARY AND COMMENT
Inflammatory response to vaccination affected participants' sense of well-being and activated specific cortical regions but did not worsen cognitive performance.
Reviewing:
Harrison NA et al., Biol Psychiatry 2009 Sep 1; 66:415
Harrison NA et al., Biol Psychiatry 2009 Sep 1; 66:407
