Lithium and Chronic Kidney Disease
SUMMARY AND COMMENT
These authors provide detailed advice on monitoring and treating patients who take lithium.
Reviewing:
Kripalani M et al., BMJ 2009 Jul 3; 339:b2452
The Right ADHD Dose
SUMMARY AND COMMENT
A second-opinion Medicaid program reduces overuse of ADHD medications.
CME
Reviewing:
Thompson JN et al., J Am Acad Child Adolesc Psychiatry 2009 Jul; 48:740
The FDAs SSRI Warning: "Were from the Government, and Were Here to Help"?
SUMMARY AND COMMENT
The FDAs black-box warning about juvenile suicidality and SSRIs might have had unintended consequences: Prescription rates and depression diagnoses, including in adults, have decreased significantly.
Reviewing:
Libby AM et al., Arch Gen Psychiatry 2009 Jun; 66:633
Brain Receptors in Schizophrenia: Its Not Just About Dopamine and Serotonin
SUMMARY AND COMMENT
June 29, 2009
Joel Yager, MD
Another study of metabotropic glutamate receptors strengthens the case for developing new types of antipsychotic medications.
Reviewing:
Ghose S et al., Am J Psychiatry 2009 Jun 1
Worrying About Alzheimer Disease? Dont!
SUMMARY AND COMMENT
In this animal model of AD, chronic stress worsened the impact of amyloid-β on learning, memory, and electrophysiologic response.
Reviewing:
Srivareerat M et al., Biol Psychiatry 2009 Jun 1; 65:918
Alberini CM., Biol Psychiatry 2009 Jun 1; 65:916
Debunking the Serotonin Gene–Life Stress Hypothesis?
SUMMARY AND COMMENT
A meta-analysis finds little evidence that gene–environment interaction increases risk for depression.
CME
Reviewing:
Risch N et al., JAMA 2009 Jun 17; 301:2462
Is Binge Eating Always the Same Problem?
SUMMARY AND COMMENT
Bulimia and binge-eating disorder are associated with different physiologic and psychological reactions to food.
Reviewing:
Schienle A et al., Biol Psychiatry 2009 Apr 15; 65:654
Adding ADHD to Bipolar Disorder in Adults: A Volatile Mixture
SUMMARY AND COMMENT
June 22, 2009
Joel Yager, MD
Even if it disappears in adulthood, ADHD in childhood suggests a more difficult course of bipolar disorder.
Reviewing:
Rydén E et al., Acta Psychiatr Scand 2009 May 7
The Environment and Depressive Symptoms in Older Adults
SUMMARY AND COMMENT
June 22, 2009
Joel Yager, MD
Neighborhood characteristics may contribute to risk for depressive symptoms.
Reviewing:
Beard JR et al., Am J Public Health 2009 Jul; 99:1308
Inhibit Histone Deacetylase Type 2 to Improve Memory?
SUMMARY AND COMMENT
Results from an animal study might indicate a new research avenue.
Reviewing:
Guan J-S et al., Nature 2009 May 7; 459:55