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Reader Remarks on:

Morphine and PTSD Risk in Injured Combat Veterans

• ptsd
• Morphine and PTSD prevention
• Morphine & PTSD
• A response from JW Psychiatry Editor-in-Chief Peter Roy-Byrne
• opioid system in PTSD pathophysiology

ptsd

m r mccutcheon, 14 Jan 2010 10:16 AM EST

Competing interests: None declared

wonder what effect versed or valium would have is used along with morphine?

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Morphine and PTSD prevention

Kristine M. Campbell MD, 14 Jan 2010 11:14 AM EST

Competing interests: None declared

Interesting. A study of morphine's effects on PTSD development in victims of other trauma, including psychological trauma could be helpful in teasing apart the mechanism.

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Morphine & PTSD

Virginia Snow, Lifespan.org, 14 Jan 2010 12:46 PM EST

Competing interests: None declared

Could it have the same affect with hypnotic recall of the trauma?

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A response from JW Psychiatry Editor-in-Chief Peter Roy-Byrne

Peter Roy-Byrne, MD, Vice-Chair & Prof., Dept. of Psychiatry and Behavioral Sciences, Univ. of Washington, Seattle, 22 Jan 2010 1:49 PM EST

Competing interests: Summary author

Studies suggest that benzodiazepines -- orally administered daily in the first few weeks after trauma -- have the OPPOSITE effect in traumatized individuals (i.e., they make things a bit worse) or no effect. I think that the results of intravenous midazolam would be the same.

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opioid system in PTSD pathophysiology

Behnia Haghiri, 30 Jan 2010 4:20 PM EST

Competing interests: None declared

On the other hand, there is a study that shows that Nalmefene, which is opioid recepter antagonist, was helpful in reducing PTSD symptoms in combat veterans

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